Antimicrobial efficacy of QMix on Enterococcus faecalis infected root canals: a systematic review of in vitro studies
Lim Benjamin Syek Hur, Parolia Abhishek, Chia Margaret Soo Yee, Jayaraman Jayakumar, Nagendrababu Venkateshbabu,
소속 상세정보
( Lim Benjamin Syek Hur ) - International Medical University School of Dentistry
( Parolia Abhishek ) - International Medical University School of Dentistry Department of Clinical Dentistry
( Chia Margaret Soo Yee ) - International Medical University School of Dentistry
( Jayaraman Jayakumar ) - University of Texas Health School of Dentistry Department of Developmental Dentistry
( Nagendrababu Venkateshbabu ) - International Medical University School of Dentistry Department of Clinical Dentistry
Abstract
Objectives: This study aimed to summarize the outcome of in vitro studies comparing the antibacterial effectiveness of QMix with other irrigants against Enterococcus faecalis.
Materials and Methods: The research question was developed by using population, intervention, comparison, outcome, and study design framework. The literature search was performed using 3 electronic databases: PubMed, Scopus, and EBSCOhost until October 2019. The additional hand search was performed from the reference list of the eligible studies. The risk of bias of the studies was independently appraised using the revised Cochrane Risk of Bias tool (RoB 2.0).
Results: Fourteen studies were included in this systematic review. The overall risk of bias for the selected studies was moderate. QMix was found to have a higher antimicrobial activity compared to 2% sodium hypochlorite (NaOCl), 17% ethylenediaminetetraacetic acid (EDTA), 2% chlorhexidine (CHX), mixture of tetracycline isonomer, an acid and a detergent (MTAD), 0.2% Cetrimide, SilverSol/H2O2, HYBENX, and grape seed extract (GSE). QMix had higher antibacterial efficacy compared to NaOCl, only when used for a longer time (10 minutes) and with higher volume (above 3 mL).
Conclusions: QMix has higher antibacterial activity than 17% EDTA, 2% CHX, MTAD, 0.2% Cetrimide, SilverSol/H2O2, HYBENX, GSE and NaOCl with lower concentration. To improve the effectiveness, QMix is to use for a longer time and at a higher volume.
키워드
Chlorhexidine; Enterococcus faecalis; QMix; root canal treatment; systematic review
원문 및 링크아웃 정보
등재저널 정보